Z. Jiang et al. “Effect of icariin on cyclic GMP levels and on the mRNA expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in penile cavernosum.” Journal of Huazhong University of Science and Technology September 2006, Volume 26, Issue 4, pp 460–462
Ying Pan et al. “Icariin from Epimedium brevicornum attenuates chronic mild stress-induced behavioral and neuroendocrinological alterations in male Wistar rats” Pharmacology Biochemistry and Behavior Volume 87, Issue 1, May 2007, Pages 130–140
Effetti analgesici, antispasmodici e vasodilatatori:
J.W. Ho et al. “Pharmacological Activity of Cardiovascular Agents from Herbal Medicine” Cardiovascular & Hematological Agents in Medicinal Chemistry Volume 5, Number 4, October 2007, pp. 273-277(5)
Andersen, T., et al. “Weight loss and delayed gastric emptying following a South American herbal preparation in overweight patients.” J. Hum. Nutr. Diet. 2001; 14(3): 243–50.
Effetti protettivi adattogenici:
Ying Pan et al.. “Impaired hypothalamic insulin signaling in CUMS rats: Restored by icariin and fluoxetine through inhibiting CRF system.” Psychoneuroendocrinology Volume 38, Issue 1, January 2013, Pages 122–134
Shindel AW, Xin Z-C, Lin G, Fandel TM, Huang YC, Banie L, Breyer BN, Garcia MM, Lin C-S, and Lue TF. Erectogenic and neurotrophic effects of icariin, a purified extract of horny goat weed (Epimedium spp.) in vitro and in vivo. J Sex Med 2010;7:1518–1528.
H. Cheng et al. “Structural characterization and antioxidant activities of polysaccharides extracted from Epimedium acuminatuml.” Carbohydrate Polymers
Volume 92, Issue 1, 30 January 2013, Pages 63–68